It elaborates the definitions of epimer and epimerization, states the applications of epimerization in medicine and pesticide,and points out its expansive prospect .

阐述了差体和差化的定义。差化技术在医药和农药中间体中应用广,前景广阔。

RESULTS The chlortetracycline's epimer, tetracycline and its epimer, as impurities in chlortetracycline have been determined by the liquid chromatogram and its first order mass spectrum.

结果得到金霉素样品液相色及液相色峰对应的一级质。对进行分析归纳,推测金霉素样品中含有四环素、差四环素和差金霉素杂质组分。