Methylmalonic acidemia is an inherited metabolic disorder,which is caused by deficiency of methylmalonyl-coenzyme A mutase or its cofactor adenosylcobalamin.

二酸血症是由于二酰辅酶A变位酶或其辅酶腺苷钴胺素缺陷所致的一种遗传性谢疾病。

Prosthetic enzyme of mutase, catalyze reactions of group, mainly methyl, metachoresis in the interior of substrate molecule.

变位酶的辅酶，催化底物分子内团(主要为)的变位。