Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以克拉霉素为起,经水解、乙酰化、环碳酸酯化、氧化、脱碳酸酯化、酰化、环基甲酸酯化和环合等反应合成目标化合物。